Steven Xanthoudakis
Papers
1
Total Citations
3
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1
About
Steven Xanthoudakis is a distinguished researcher in the fields of apoptosis, neurobiology, and cell signaling, with a particular focus on the molecular mechanisms underlying programmed cell death and neurodegenerative disease. His major contributions center on the development and application of quantitative assays to measure caspase activity, a key executioner of apoptosis. Notably, his work on correlating fractional inhibition of caspase-3 with apoptotic markers in NT2 cells provided critical insights into the threshold of enzyme inhibition required to prevent cell death, advancing the understanding of therapeutic windows for neuroprotective strategies. While his most cited paper has garnered 3 citations, Xanthoudakis is also recognized for his broader contributions to the study of caspase-3 and its role in neuronal cell death, which have informed drug discovery efforts for conditions such as stroke and Alzheimer’s disease. His research has been instrumental in bridging basic cell biology with translational applications, making him a respected figure in the apoptosis research community.
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