Yanhe Ma

Papers

Total Citations

184

H-Index

About

Yanhe Ma is a pioneering figure in synthetic biology and metabolic engineering, with a focus on developing cutting-edge genetic tools for industrial microorganisms. His most notable contribution is the invention of MACBETH (Multiplex Automated Corynebacterium glutamicum Base Editing Method), a revolutionary platform that enables efficient, multiplexed genome editing in *Corynebacterium glutamicum*—a workhorse for amino acid and biochemical production. This 2018 study, which has garnered 184 citations, transformed strain engineering by allowing rapid, precise, and high-throughput base modifications without double-strand breaks, dramatically accelerating the design of microbial cell factories. Ma’s research bridges fundamental molecular biology and applied biotechnology, addressing challenges in sustainable chemical manufacturing. His work has been instrumental in advancing the production of valuable compounds like lysine and succinic acid, with broad implications for green chemistry and bioprocessing. Recognized for his innovative approach, Ma continues to shape the field through tools that empower researchers to rewire microbial metabolism with unprecedented speed and accuracy, making him a key figure in the next generation of industrial biotechnology.