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About

Y. Grassano is a leading figure in urologic oncology, specializing in the surgical management of renal tumors, with a particular focus on robotic and minimally invasive techniques. His most impactful work centers on optimizing partial nephrectomy outcomes, where he has made seminal contributions to reducing warm ischemia time—a critical factor in preserving kidney function. His landmark study, "Comparison of 1800 Robotic and Open Partial Nephrectomies for Renal Tumors" (179 citations), provided robust, large-scale evidence demonstrating the safety and efficacy of the robotic approach. Grassano further advanced the field by pioneering and validating the early unclamping technique during robot-assisted partial nephrectomy (78 citations), showing it can significantly minimize warm ischemia without increasing morbidity. His research also includes important comparative analyses of partial nephrectomy versus ablative therapy and off-clamp versus on-clamp robotic techniques (23 citations), offering surgeons evidence-based strategies for diverse clinical scenarios. Through these contributions, Grassano has shaped modern nephron-sparing surgery, helping to establish robotic partial nephrectomy as a standard of care for renal tumors.