Vania Yotova
Papers
1
Total Citations
76
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1
About
Dr. Vania Yotova is a molecular geneticist whose pioneering work in pharmacogenomics has significantly advanced the rapid detection of genetic variants affecting drug metabolism. Her most-cited study, published in 1999, introduced a groundbreaking multiplex polymerase chain reaction and allele-specific oligonucleotide assay for simultaneously identifying polymorphisms in CYP1A1, CYP2D6, and NAT genes—key players in the metabolism of numerous therapeutics and carcinogens. This methodological innovation, which has garnered 76 citations, provided a faster, more efficient tool for personalized medicine, enabling clinicians to predict patient responses to drugs and assess susceptibility to certain cancers. Dr. Yotova’s contributions have laid critical groundwork for the development of high-throughput genotyping platforms, directly impacting fields from oncology to toxicology. Her work remains a cornerstone for researchers exploring genetic variability in drug metabolism, underscoring her lasting influence on the transition from one-size-fits-all treatment to tailored therapeutic strategies.
Research Focus
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Top Papers
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