Tomoki Yoshihara
Papers
1
Total Citations
11
H-Index
1
About
Tomoki Yoshihara is a pioneering researcher at the intersection of bioanalytics and therapeutic antibody discovery, with a core focus on advancing high-throughput flow cytometry for drug development. His most influential work, "Automated High-Throughput Flow Cytometry for High-Content Screening in Antibody Development" (2018, 11 citations), directly addresses a critical bottleneck in biopharmaceutical research: the labor-intensive sample preparation that historically limited flow cytometry's utility as a primary screening method. By engineering an automated, high-content workflow, Yoshihara transformed flow cytometry from a low-throughput analytical tool into a robust platform capable of handling the massive sample volumes required for modern antibody discovery. This innovation enables researchers to screen thousands of antibody candidates with the sensitivity and accuracy of traditional flow cytometry, dramatically accelerating the identification of therapeutic leads. His contributions are particularly timely given the surging demand for antibody-based therapeutics in oncology, immunology, and infectious disease. Yoshihara’s work has been recognized for bridging the gap between cutting-edge instrumentation and practical drug discovery pipelines, making him a key figure in the evolution of high-content screening technologies.
Research Focus
Key Achievements
Top Papers
- 1