Papers
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Total Citations
185
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About
Tami Hood is a pioneering researcher in chemical biology and drug discovery, best known for developing high-throughput platforms that bridge the gap between molecular libraries and functional cellular insights. Her landmark 2006 paper, “An efficient rapid system for profiling the cellular activities of molecular libraries,” has garnered 185 citations and introduced a transformative approach for rapidly characterizing small molecules, peptides, proteins, and RNAs across a broad spectrum of cellular assays. This work enabled researchers to uncover novel biological activities and generate comprehensive activity profiles for drug candidates early in the development pipeline—a critical advance for reducing late-stage attrition. Hood’s contributions have accelerated the identification of bioactive compounds and provided a scalable framework for functional genomics and chemical genetics. Her system remains a foundational tool for profiling cellular responses, influencing both academic labs and pharmaceutical R&D. By merging speed with biological relevance, Hood has empowered scientists to move beyond simple target-based screens toward a more holistic understanding of molecular function in living systems.
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Top Papers
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