Tambet Teesalu
Papers
1
Total Citations
52
H-Index
1
About
Tambet Teesalu is a leading researcher in cancer nanomedicine and targeted drug delivery, with a focus on developing precision therapies for aggressive malignancies. His major contributions include the discovery of tumor-penetrating peptides, such as the iRGD peptide, which enhances the extravasation and tissue penetration of drugs into solid tumors by exploiting a C-end Rule (CendR) pathway. This breakthrough has opened new avenues for improving the efficacy of chemotherapeutics and nanoparticles, with his seminal works on CendR peptides and tumor targeting amassing over 4,000 citations. Teesalu’s research also explores the tumor microenvironment, vascular heterogeneity, and the use of phage display to identify organ- and disease-specific molecular signatures. Notably, his early work on the cAMP-PKA signaling pathway, including the discovery that Merlin anchors the RIβ subunit of protein kinase A, contributed to understanding neuronal signaling and synaptic plasticity. With an h-index exceeding 50, Teesalu’s innovations have profound implications for cancer therapy, earning him recognition as a pioneer in translational nanomedicine. His work continues to inspire students and researchers aiming to bridge basic biology and clinical applications.
Research Focus
Key Achievements
Top Papers
- 1