Sung Hwan Kang
Papers
1
Total Citations
59
H-Index
1
About
Dr. Sung Hwan Kang is a structural biologist whose pioneering work has illuminated the molecular machinery of the ubiquitin-fold modifier 1 (Ufm1) system, a critical but less-explored pathway in cellular protein modification. His landmark 2008 study, cited 59 times, provided the first structural basis for how the protease UfSP1 processes the Ufm1 precursor, revealing the precise mechanism that exposes its C-terminal glycine for conjugation—a fundamental step for Ufm1 activation. By solving the crystal structure of UfSP1 in complex with Ufm1, Dr. Kang demonstrated how this novel protease recognizes and cleaves the precursor with high specificity, distinguishing it from other deubiquitinating enzymes. This work not only advanced our understanding of Ufm1 biology but also established a framework for studying its roles in cellular stress responses and disease. Dr. Kang’s contributions have been instrumental in opening new avenues for research into ubiquitin-like protein pathways, making him a key figure in structural biochemistry and a valuable resource for students exploring the diversity of post-translational modifications.
Research Focus
Key Achievements
Top Papers
- 1Structural Basis for Ufm1 Processing by UfSP159 citations · 2008