Stephanie Holst
Papers
1
Total Citations
92
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1
About
Stephanie Holst is a leading figure in glycobiology, with her research centered on the development of high-throughput analytical methods for the comprehensive characterization of the human N-glycome. Her major contribution lies in pioneering robust, linkage-specific sialic acid esterification techniques for mass spectrometry, which allow for the precise discrimination of α2,3- and α2,6-linked sialic acids—a critical distinction in disease biomarker discovery. Her landmark 2015 paper, "Automation of High-Throughput Mass Spectrometry-Based Plasma N-Glycome Analysis with Linkage-Specific Sialic Acid Esterification," has garnered 92 citations, establishing a gold-standard workflow for plasma glycan profiling. This work, alongside her other highly cited studies, has significantly advanced the field by enabling reproducible, large-scale glycomic analysis, directly impacting our understanding of glycosylation’s role in inflammation and cancer. Holst’s methodological innovations have been instrumental in translating complex glycan structures into clinically actionable data, making her a pivotal researcher for any student or scientist interested in the intersection of analytical chemistry and disease biology.
Research Focus
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Top Papers
- 1