Stell Santiago

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About

Stell Santiago is a rising clinician-scientist whose research focuses on the intersection of head and neck oncology, viral oncology, and liquid biopsy diagnostics. Dr. Santiago’s most notable contribution to date is a pioneering pilot study on the use of human papillomavirus circulating tumor DNA (ctHPVDNA) as a diagnostic tool for squamous cell carcinoma of unknown primary. This work addresses a critical clinical challenge—identifying occult HPV-related oropharyngeal cancers in patients presenting with cervical neck metastases. By demonstrating the diagnostic accuracy of ctHPVDNA assays, Santiago’s research offers a non-invasive, targeted approach that could transform the workup for these patients, potentially reducing the need for extensive, invasive biopsies. Though early in its citation history, this 2024 study has already garnered 10 citations, signaling its immediate relevance and impact within the field. Dr. Santiago’s work bridges molecular biology and clinical practice, positioning them as a key voice in the emerging era of precision oncology for head and neck cancers. Their contributions hold promise for improving diagnostic speed, accuracy, and patient outcomes in this challenging disease.