Sophie Deneuve
Papers
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Total Citations
1
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About
Sophie Deneuve is a leading head and neck surgeon-oncologist whose research focuses on improving diagnostic precision and treatment outcomes for patients with head and neck cancers of unknown primary (CUP). Her major contributions center on advancing minimally invasive surgical techniques to identify occult primary tumors, thereby enabling more targeted radiotherapy and reducing treatment-related morbidity. Deneuve is best known for her work on the RoboCUP trial, a randomized phase 2 protocol comparing transoral robotic surgery (TORS) and transoral laser microsurgery (TLM) for bilateral tongue base mucosectomy combined with tonsillectomy. This landmark study, published in 2025, has already garnered 1 citation and represents a critical step toward standardizing the diagnostic workup for CUP. Her research directly addresses the challenge of locating hidden primary tumors in patients presenting with cervical lymphadenopathy, allowing for smaller radiation fields and improved quality of life. Deneuve’s work bridges surgical innovation and oncologic precision, making her a pivotal figure in the evolving landscape of head and neck cancer care.
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