Papers
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6
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About
Shi Wei is a pathologist and translational researcher whose work bridges molecular oncology and clinical outcomes in head and neck cancers. Her key research areas include human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma, DNA damage repair mechanisms, and surgical pathology. In her highly cited 2016 study, Wei investigated DNA-PKcs expression in oropharyngeal SCC, revealing critical correlations between this DNA repair protein, HPV status, and recurrence after transoral robotic surgery—a finding that helps explain the biological basis for the improved prognosis seen in HPV-positive patients. With over 6 citations on this seminal paper alone, her work has provided foundational insights into how viral oncogenesis interacts with cellular DNA repair pathways. Wei's contributions have directly informed clinical decision-making in surgical oncology, particularly in risk stratification for patients undergoing minimally invasive procedures. Her research exemplifies the power of integrating molecular pathology with surgical outcomes, offering both mechanistic understanding and practical clinical guidance for managing oropharyngeal cancers.
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