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About

Sasan Jalili‐Firoozinezhad is a pioneering figure in the field of organ-on-a-chip technology, where his work bridges engineering and human physiology to revolutionize drug development. His key research centers on creating vascularized organ chips and developing automated platforms that mimic human systemic interactions. Jalili‐Firoozinezhad’s major contributions include the quantitative prediction of human pharmacokinetic responses using fluidically coupled vascularized organ chips, a breakthrough that earned 463 citations for its potential to replace animal testing. He also co-developed the “Interrogator”—a robotic platform for fluidically-linked human body-on-chips experimentation. This system, described in a foundational 2019 paper, uses liquid-handling robotics, custom software, and an integrated mobile microscope to automate culture, perfusion, and imaging of up to ten Organ Chips simultaneously. His work on robotic fluidic coupling and interrogation of multiple vascularized organ chips (401 citations) further demonstrates his impact, enabling high-throughput, human-relevant drug screening. Jalili‐Firoozinezhad’s innovations are shaping the future of personalized medicine and toxicology, offering unprecedented precision in modeling human biology outside the body.