Papers
1
Total Citations
14
H-Index
1
About
Sara Orecchia is a leading colorectal surgeon whose research centers on optimizing surgical timing and minimally-invasive approaches for rectal cancer treatment. Her most impactful work stems from the TiMiSNAR trial, a landmark multicenter randomized controlled study comparing standard 8-week versus prolonged 12-week intervals between neoadjuvant chemoradiotherapy and minimally-invasive surgery. This investigation addresses a critical clinical controversy: whether extending the waiting period allows for more complete tumor regression before resection. With 14 citations, this trial has shaped contemporary surgical protocols by providing Level I evidence on timing strategies. Orecchia’s contributions extend to refining laparoscopic and robotic techniques, emphasizing patient outcomes and pathological response rates. Her work bridges oncology and surgery, demonstrating that delayed intervention may enhance tumor downstaging without compromising safety. As a researcher, she has advanced personalized treatment timelines in rectal cancer, influencing international guidelines. Orecchia’s dedication to rigorous trial design and translational impact makes her a key figure in colorectal oncology, offering surgeons and patients evidence-based decisions for timing surgery after chemoradiation.
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