Sander van den Driesche
Papers
1
Total Citations
5
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1
About
Sander van den Driesche is a microsystems engineer whose research bridges bioanalytical chemistry and lab-on-a-chip technology, with a focus on artificial lipid bilayer platforms for studying membrane transport. His work addresses the critical challenge of investigating antibiotic uptake through bacterial porins, which has direct implications for understanding antimicrobial resistance. In his notable 2018 study on "Fast Formation of Lipid Bilayer Membranes for Simultaneous Analysis of Molecular Transport Using Parylene Coated Chips," van den Driesche introduced an innovative silicon chip design featuring Parylene-C coated silicon nitride to enable rapid, parallelized formation of stable lipid bilayers. This approach overcomes traditional limitations of low sample volumes and poor scalability, allowing for simultaneous analysis of molecular transport across membranes. While his citation counts remain modest—reflecting the specialized nature of his work—his contributions are significant for researchers developing high-throughput screening tools for antibiotic permeability. Van den Driesche’s engineering solutions have advanced the practical utility of artificial bilayers, making them more accessible for studying channel-forming proteins and drug transport mechanisms, a critical step in combating bacterial resistance.
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Top Papers
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