Ramesh Kuppusamy
Papers
1
Total Citations
53
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1
About
Ramesh Kuppusamy is a leading figure in non-invasive prenatal diagnostics, with a primary research focus on fetal RHD genotyping using cell-free fetal DNA from maternal plasma. His landmark 2011 study, cited 53 times, demonstrated the feasibility of accurately determining fetal RhD status as early as 11–13 weeks of gestation. By employing a high-throughput robotic technique on stored plasma samples from 591 RhD-negative women, Kuppusamy’s work established a robust, scalable method that significantly reduces the need for invasive procedures like amniocentesis. This contribution has profound implications for managing RhD incompatibility in pregnancy, enabling early intervention to prevent hemolytic disease of the newborn. His research bridges molecular genetics and clinical obstetrics, offering a safer, more efficient pathway for prenatal screening. Kuppusamy’s achievements underscore his role in advancing precision medicine in maternal-fetal health, with his methodology now influencing global screening protocols. For students and researchers, his work exemplifies how translational science can directly improve patient care, making him a pivotal figure in the evolution of non-invasive prenatal testing.
Research Focus
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Top Papers
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