Purnima Deshpande
Papers
1
Total Citations
56
H-Index
1
About
Purnima Deshpande’s research centers on DNA sequencing methodology, with a particular focus on improving accuracy and reliability in genomic analysis. Her most-cited work, a 1993 study on sequence length and error analysis, systematically compared two foundational sequencing techniques—manual Sequenase reactions and automated Taq cycle sequencing—using fragments from a 35.3-kilobase cosmid insert. By examining error rates as a function of sequence length, Deshpande provided critical insights into the limitations and strengths of these methods at a time when large-scale sequencing was rapidly evolving. This work, which has garnered 56 citations, helped guide researchers in selecting appropriate protocols for their projects, contributing to the broader effort to enhance sequencing fidelity. Her contributions reflect a meticulous approach to method validation, essential for the accuracy of subsequent genomic discoveries. Deshpande’s research remains a reference point for those studying the technical challenges of early DNA sequencing, underscoring her role in advancing the tools that underpin modern genomics.
Research Focus
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Top Papers
- 1