Linda Rowan
Papers
1
Total Citations
56
H-Index
1
About
Linda Rowan’s research has been instrumental in advancing the accuracy and reliability of DNA sequencing methods, a cornerstone of modern genomics. Her most-cited work, a 1993 study with 56 citations, provides a rigorous comparative analysis of sequence error rates across two foundational techniques: manual sequencing with Sequenase and automated Taq cycle sequencing. By systematically examining error as a function of sequence length, Rowan’s study offered critical benchmarks for data quality, helping researchers choose appropriate methods for projects ranging from small-scale cloning to large genome assembly. This contribution was particularly valuable during the early era of high-throughput sequencing, where understanding error profiles was essential for interpreting genetic data. Beyond this key paper, Rowan’s expertise in molecular biology techniques has supported the accurate characterization of complex DNA fragments, including the sequencing of a 35.3 kb cosmid insert. Her work remains a reference point for scientists navigating the trade-offs between manual and automated sequencing, underscoring her lasting impact on the field’s methodological rigor.
Research Focus
Key Achievements
Top Papers
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