Polina Mamoshina

Johns Hopkins University

Papers

1

Total Citations

600

H-Index

1

About

Polina Mamoshina is a pioneering computational biologist whose work sits at the intersection of artificial intelligence, drug discovery, and aging research. She is best known for her groundbreaking contributions to applying deep learning to pharmacology, most notably in her highly cited 2016 paper (600 citations) that demonstrated how deep neural networks trained on large transcriptional response datasets can predict drug properties and enable drug repurposing. This work established a powerful new paradigm for using transcriptomic data to accelerate pharmaceutical development. Mamoshina has also made significant contributions to the emerging field of deep aging clocks, using AI to analyze blood biochemistry and transcriptomic data to predict biological age and assess the effects of various interventions on aging. Her research has been instrumental in showing how machine learning can identify biomarkers of aging and evaluate potential geroprotective drugs. With her work spanning both computational methods and practical biomedical applications, Mamoshina continues to be a leading voice at the forefront of AI-driven longevity research and precision medicine.

Research Focus

Key Achievements

1
H-Index
1
Papers
600
Total Citations
600
Avg Citations/Paper
🏆 Most Cited Paper
Deep Learning Applications for Predicting Pharmacological Properties of Drugs and Drug Repurposing Using Transcriptomic Data
600 citations · 2016
📈 Most Prolific Year: 2016 (1 Papers)
🤝 Key Collaborators: 5
🏛 Institutions: Johns Hopkins University

Top Papers

  1. 1

Key Collaborators

Contact & Links

Available for collaboration
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