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About

Pei-Yong Shi is a leading virologist whose research focuses on the molecular biology and pathogenesis of emerging flaviviruses and coronaviruses, with a particular emphasis on West Nile virus (WNV) and SARS-CoV-2. His major contributions include pioneering high-throughput detection methods for WNV RNA, a breakthrough that has been cited over 240 times and has become essential for global surveillance and outbreak response. More recently, Dr. Shi has been at the forefront of COVID-19 research, developing an integrated research-clinical BSL-2 platform for a live SARS-CoV-2 neutralization assay. This innovative work, leveraging highly attenuated virus strains, enables safe, efficient, and scalable monitoring of neutralizing antibodies against SARS-CoV-2 and its variants of concern. His efforts have directly supported public health responses and vaccine evaluation. With a career marked by translational impact, Dr. Shi’s work bridges fundamental virology and clinical application, making him a pivotal figure in pandemic preparedness and antiviral development.