Paolo Berretta

About

Paolo Berretta is a leading figure in minimally invasive cardiac surgery, with a focused expertise in mitral and tricuspid valve procedures. His major contributions stem from his pivotal role in the "mini-mitral international registry" (MMIR), the largest global dataset of its kind. Through this work, he has provided critical insights into the safety and efficacy of minimally invasive approaches. His landmark 2023 study, cited 31 times, established a direct correlation between aortic cross-clamp time and patient mortality, offering a crucial benchmark for surgical teams worldwide. Berretta has also advanced the field by rigorously comparing direct vision versus fully endoscopic techniques, as detailed in his 2025 analysis of over 7,500 patients. This research helps define best practices for surgical access, balancing operative precision with patient outcomes. By leveraging large-scale, real-world data, Berretta’s work is not only shaping current surgical protocols but also setting the stage for safer, less invasive cardiac care.

Research Focus

Key Achievements

Top Papers

1. 1
   Aortic cross-clamp time correlates with mortality in the mini-mitral international registry

   31 citations · 2023
2. 2
   Endoscopic and direct vision approaches in minimally-invasive mitral and tricuspid valve surgery – insights from the mini-mitral registry

   3 citations · 2025

Key Collaborators

Contact & Links