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About

Manuel Wilbring is a leading figure in minimally invasive cardiac surgery, with a particular focus on mitral and tricuspid valve procedures. His major contributions center on analyzing large-scale, international patient data to refine surgical techniques and improve patient outcomes. Wilbring is a key investigator in the Mini-Mitral International Registry (MMIR), the largest registry of its kind, where his work has provided critical insights into the relationship between operative factors and mortality. His highly cited 2023 study, with 31 citations, established that prolonged aortic cross-clamp time is a significant predictor of mortality in minimally invasive valve surgery, a finding that directly influences surgical strategy and training. More recently, his 2025 analysis of over 7,500 patients compared direct vision with endoscopic approaches, offering vital guidance on the safety and efficacy of different minimally invasive access methods. Through these landmark registry analyses, Wilbring has helped define best practices and safety benchmarks for the modern cardiac surgeon, making his work essential reading for anyone in the field.