Oxana P. Trifonova
Papers
1
Total Citations
3
H-Index
1
About
Oxana P. Trifonova’s research centers on proteomics and the molecular characterization of human health, with a particular focus on the low-molecular-weight subproteome of blood serum. Her major contribution lies in systematically mapping the natural variability of this subproteome in healthy individuals, establishing a critical baseline for distinguishing normal physiological fluctuations from disease-associated changes. In her most cited work (3 citations), she analyzed serum proteome profiles across three age groups—20–30, 30–40, and 40–50 years—demonstrating how interindividual differences and age-related shifts shape the circulating protein landscape under normal vital activity. This foundational study provides essential reference data for biomarker discovery, ensuring that future diagnostic efforts account for inherent biological variability. Trifonova’s meticulous approach underscores the importance of defining “healthy” proteomes before searching for disease signatures, a principle that strengthens the reliability of clinical proteomics. Her work is particularly valuable for students and researchers in biomarker development, as it highlights the need for rigorous controls in translational studies. By quantifying the range of normal variation, Trifonova has helped lay the groundwork for more accurate, personalized diagnostic tools.
Research Focus
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Top Papers
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