Oriana Ciani
Papers
3
Total Citations
49
H-Index
3
About
Oriana Ciani is a leading health economist and methodologist whose work sits at the intersection of real-world evidence (RWE) and health technology assessment (HTA), with a particular focus on medical devices and oncology. Her research systematically evaluates how real-world data (RWD) can be harnessed to support regulatory and reimbursement decisions. Her highly cited 2021 paper, "Do existing real-world data sources generate suitable evidence for the HTA of medical devices in Europe?," provides a critical framework for mapping and appraising RWD sources, directly addressing a major bottleneck in the field. This work, alongside her incisive commentary on the distinction between statistical and clinical significance in surgical trials, demonstrates her commitment to methodological rigor in evidence synthesis. Ciani is also the principal investigator of the LUCENT study, a major Italian observational initiative designed to capture real-world outcomes for patients with early and locally advanced non-small cell lung cancer (NSCLC). Through this work, she is generating critical evidence on evolving treatment paradigms, directly informing clinical practice and policy. With over 40 citations on her foundational RWE paper alone, Ciani’s contributions are shaping how researchers and decision-makers leverage real-world data to improve patient access to innovative technologies.
Research Focus
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Top Papers
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