Nicolle H. Packer
Papers
1
Total Citations
73
H-Index
1
About
Nicolle H. Packer is a pioneering figure in glycoproteomics and proteomics, whose work has fundamentally advanced the understanding of protein glycosylation and its functional roles in health and disease. Her research integrates high-throughput mass spectrometry with innovative chemical printing strategies, as exemplified by her seminal 2002 paper on peptide mass fingerprinting and protein macroarray analysis, which has garnered over 73 citations. This work introduced a piezoelectric microdispensing system for rapid, non-contact fluid delivery, enabling the efficient digestion and analysis of human plasma and platelet proteins—a technique that has become foundational for large-scale proteomic studies. Packer’s major contributions include the development of methods for characterizing glycoproteins, revealing how sugar modifications influence protein function, cell signaling, and disease mechanisms. Her impact is reflected in a high citation count across her body of work, with many papers serving as key references in the field. Notably, she has been recognized for her leadership in the Human Proteome Organization and her role in advancing glycan analysis standards. For students and researchers, Packer’s career exemplifies how technological innovation in mass spectrometry can unlock new dimensions of molecular biology.
Research Focus
Key Achievements
Top Papers
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