Nevin Sabet
Papers
1
Total Citations
32
H-Index
1
About
Nevin Sabet is a molecular biologist whose work has significantly advanced our understanding of the intricate regulatory networks governing gene expression. Her primary research focuses on the mechanisms of pre-mRNA splicing and its interplay with other critical transcript determinants, particularly in the model organism *Saccharomyces cerevisiae*. Sabet’s most notable contribution is the development and implementation of a groundbreaking, high-throughput reverse genetic screen, detailed in her highly cited 2012 paper (32 citations). This innovative approach, which couples robotic RNA isolation and quantitative PCR with genome-wide strain analysis, allowed for the first robust, quantitative dissection of how splicing machinery connects with 5′ and 3′ end processing. By revealing novel genetic connections between these fundamental processes, Sabet’s work provides a powerful platform for systems-level analysis of RNA biology. Her methodological contributions have established a new standard for high-throughput functional genomics, offering researchers a scalable tool to unravel the complex logic of eukaryotic gene regulation.
Research Focus
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Top Papers
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