Narendra Padhan
Papers
1
Total Citations
12
H-Index
1
About
Narendra Padhan is a molecular biologist whose research centers on cancer signaling pathways and biomarker discovery, with a particular focus on colorectal cancer (CRC). His most-cited work, "High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer" (2016, 12 citations), introduces a novel methodological approach to detect aberrant EGFR and Ras pathway signaling—key drivers of CRC progression involving recurrent amplifications and mutations in EGFR, KRAS, and BRAF. By employing high-sensitivity isoelectric focusing, Padhan developed a technique capable of identifying subtle phosphorylation changes that serve as functional biomarkers for constitutive pathway activation. This contribution addresses a critical gap in CRC diagnostics, where genetic mutations alone often fail to predict signaling activity. His work bridges molecular pathology and clinical application, offering a potential tool for earlier and more precise diagnosis. Padhan’s research underscores the importance of integrating advanced proteomic methods with genetic insights to unravel cancer mechanisms, making his findings valuable for both basic scientists and clinicians seeking to improve patient stratification and targeted therapy outcomes.
Research Focus
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Top Papers
- 1