Najam A. Sharif
Papers
1
Total Citations
22
H-Index
1
About
Dr. Najam A. Sharif is a leading figure in ocular pharmacology, whose research has fundamentally advanced our understanding of prostaglandin receptors and their role in treating glaucoma. His work centers on the molecular mechanisms of intraocular pressure regulation, particularly through the activation of DP, EP2, and IP receptors. Sharif’s major contributions include pioneering the use of semi-automated, robotic radioimmunoassay techniques to quantify cAMP signaling in human ocular cells—a methodological breakthrough that enabled precise, high-throughput screening of receptor-specific drugs. This work, exemplified by his highly cited 1998 paper (22 citations), laid the groundwork for developing novel glaucoma therapies that target these pathways with greater efficacy and fewer side effects. Beyond his laboratory innovations, Sharif has been instrumental in translating basic receptor biology into clinical applications, earning recognition for his sustained impact on vision science. His research continues to shape how we approach ocular hypertension, offering new hope for patients through targeted, receptor-selective treatments.
Research Focus
Key Achievements
Top Papers
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