Mihnea Bostina
Papers
1
Total Citations
80
H-Index
1
About
Dr. Mihnea Bostina is a leading structural biologist whose research focuses on elucidating the molecular architecture of large macromolecular complexes, particularly those central to mitochondrial bioenergetics and disease. His landmark work on the membrane-bound NADH:ubiquinone oxidoreductase (Complex I) has provided critical insights into the function of this key respiratory chain enzyme, which is the primary site of mitochondrial radical production and a major player in numerous mitochondrial pathologies. His 2003 study, which has garnered 80 citations, revealed an unexpected position for the 49-kDa subunit of Complex I, offering novel functional implications and advancing our understanding of its molecular mechanism at a time when structural information was scarce. This foundational contribution has helped shape the field of mitochondrial biology. Dr. Bostina’s work continues to bridge the gap between structure and function, making him a pivotal figure for students and researchers interested in the molecular underpinnings of cellular energy metabolism and mitochondrial disease.
Research Focus
Key Achievements
Top Papers
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