Michela De Santis
Papers
1
Total Citations
69
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1
About
Michela De Santis is a leading figure in the field of stereotactic radiosurgery, with a primary focus on the non-invasive treatment of trigeminal neuralgia. Her most influential work, a 2009 study on CyberKnife radiosurgery as a first-line treatment for this debilitating condition, has garnered 69 citations and established a new paradigm for patient care. In this pivotal research, De Santis demonstrated that the frameless CyberKnife system could provide a safe and effective alternative to traditional surgical interventions for pharmacologically refractory trigeminal neuralgia. By treating 33 patients with this robotic technology, she provided compelling evidence that high-dose radiation could be precisely delivered to the trigeminal nerve root, offering significant pain relief while minimizing damage to surrounding healthy tissue. Her contributions have not only expanded the therapeutic arsenal for neurosurgeons but have also improved the quality of life for countless patients suffering from chronic facial pain. De Santis’s work remains a cornerstone in the literature, influencing clinical protocols and inspiring further research into radiosurgical applications for functional disorders.
Research Focus
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