Michael K. Deyholos

About

Michael K. Deyholos is a molecular biologist whose research has made significant contributions to the field of genomics, particularly in the development and application of high-throughput gene expression technologies. His most influential work centers on DNA microarray technology, a powerful platform for simultaneously monitoring the expression of thousands of genes across entire genomes. Deyholos's 2001 paper on high-density microarrays for gene expression analysis, which has garnered 83 citations, helped establish foundational principles for detecting gene expression changes associated with critical biological processes such as morphogenesis, aging, cancer, and environmental adaptation. Building on this, his 2003 work on constructing bacterial DNA microarrays using an optimized two-stage PCR strategy — cited 33 times — provided researchers with a practical and efficient framework for global gene expression profiling directly from genomic sequence data. Taken together, his contributions have equipped molecular biologists with refined methodological tools to investigate the genetic underpinnings of complex biological phenomena. His work bridges technical innovation and biological discovery, making him a valuable figure in the genomics community whose methods have informed diverse research programs spanning microbiology, developmental biology, and disease research.

Research Focus

Key Achievements

Top Papers

1. 1
   High-density microarrays for gene expression analysis

   83 citations · 2001
2. 2
   The construction and use of bacterial DNA microarrays based on an optimized two-stage PCR strategy

   33 citations · 2003

Key Collaborators

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