Michael Breitenbach
Papers
2
Total Citations
80
H-Index
2
About
Michael Breitenbach is a researcher whose work has made meaningful contributions to the field of yeast genetics and cellular stress response. His most recognized research focuses on oxidative stress sensitivity in *Saccharomyces cerevisiae*, employing systematic phenotypic screening approaches to uncover the functional roles of specific genes within the cell. Using high-throughput microtitre plate assays and robotics, Breitenbach and colleagues screened over 600 gene deletion strains sourced from the EUROSCARF collection to identify which genes confer resistance or sensitivity to oxidative stress — a powerful strategy for linking genotype to phenotype on a genomic scale. This work, published in the early 2000s and accumulating 78 citations, helped establish scalable methodologies for functional genomics in yeast model systems, offering broader insights relevant to aging, disease, and cellular defense mechanisms. By leveraging the well-characterized FY1679 strain background, his studies provided reproducible and comparable data that continue to inform researchers investigating oxidative stress pathways. Breitenbach's contributions represent an important bridge between large-scale deletion library resources and practical biological discovery, making his work a useful reference point for students and researchers exploring yeast cell biology and stress response genetics.
Research Focus
Key Achievements
Top Papers
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