Michael Beyermann
Papers
1
Total Citations
27
H-Index
1
About
Michael Beyermann is a structural and molecular biologist whose research centers on protein–protein interactions mediated by specialized recognition domains, particularly the GYF domain. His major contributions have elucidated how adapter proteins like CD2BP2 use GYF domains to bind proline-rich sequences in key intracellular targets, bridging cell adhesion and RNA splicing machinery. His landmark 2005 study, "Novel Interaction Partners of the CD2BP2-GYF Domain" (27 citations), systematically identified previously unknown binding partners beyond the known CD2 and SmB/B′ proteins, establishing a general framework for mapping GYF domain interaction networks. This work has been foundational for understanding how modular protein domains orchestrate signaling and splicing complexes. Beyermann’s research has implications for T cell activation and spliceosome regulation, and his methodological approach continues to guide studies of proline-rich motif recognition. His findings remain cited in structural biology and immunology contexts, highlighting their enduring relevance for researchers investigating intracellular communication and protein complex assembly.
Research Focus
Key Achievements
Top Papers
- 1Novel Interaction Partners of the CD2BP2-GYF Domain27 citations · 2005