Mauro Cerretani

Institute of Molecular Biology and Pathology

Papers

Total Citations

H-Index

About

Mauro Cerretani is a biochemist whose work has significantly advanced the study of viral proteases, particularly in the context of Hepatitis C virus (HCV) drug discovery. His key research areas include enzymatic assay development, antiviral mechanisms, and high-throughput screening methodologies. Cerretani’s most notable contribution is the development of a high-throughput radiometric assay for the HCV NS3 protease, a critical enzyme in viral replication. This assay, detailed in his 1999 paper, provided a robust and scalable method for screening potential inhibitors, laying essential groundwork for subsequent antiviral drug development. With 14 citations, this work has been recognized as a foundational tool in the field, enabling researchers to efficiently identify compounds that could disrupt HCV replication. Cerretani’s expertise in assay design and his focus on practical, high-impact solutions have made him a valuable contributor to the broader effort to combat viral diseases, and his methodological innovations continue to inform modern antiviral research strategies.