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About

Matteo Lenge is a leading figure in pediatric stereotactic and functional neurosurgery, whose work bridges cutting-edge surgical technique with deep mechanistic insight into network-based brain disorders. His research centers on three key areas: stereo-electroencephalography (SEEG) for epilepsy, robot-assisted minimally invasive approaches, and deep brain stimulation (DBS) for complex neuropsychiatric and movement disorders. Lenge’s most cited work, “A Practical Approach to Stereo EEG” (2020, 17 citations), provides a foundational guide for clinicians performing SEEG, a critical tool for localizing epileptic foci. He has also pioneered novel surgical routes, as demonstrated in his technical note on robot-assisted transcerebellar stereotaxy for posterior fossa lesions in pediatric patients (2023, 6 citations). Notably, Lenge’s investigation into DBS of the subgenual cingulate region for conversion disorder with psychogenic non-epileptic seizures and catatonia (2021, 2 citations) reveals his commitment to treating “network pathologies” by targeting hub nodes in cortico-striato-thalamo-cortical loops. His multicenter work on unilateral Vim DBS for post-traumatic tremor in children (2024, 2 citations) further underscores his impact on improving outcomes for young patients with severe, treatment-resistant conditions. With a career defined by technical innovation and a deep understanding of brain circuitry, Lenge is shaping the future of pediatric functional neurosurgery.