Margaret S. Pearle
Papers
2
Total Citations
931
H-Index
2
About
Margaret S. Pearle is a world-renowned urologist whose research has fundamentally shaped the management of kidney stone disease. Her primary contributions lie in urolithiasis and endourology, where she has advanced both surgical techniques and evidence-based clinical guidelines. She is best known for her pivotal role in authoring the AUA Guideline on Management of Staghorn Calculi (2005), a landmark work cited over 900 times that established the standard diagnostic and treatment protocols for complex renal calculi. Beyond guidelines, Pearle has pioneered minimally invasive approaches, including comparative studies of laparoscopic versus open retroperitoneal lymph node dissection, demonstrating cost-effectiveness and improved patient outcomes. Her work has been instrumental in shifting practice away from open surgery toward less invasive endoscopic and laparoscopic methods. With a career spanning decades at UT Southwestern Medical Center, she has also made significant contributions to medical education and clinical trial design. Pearle’s research continues to influence urologists worldwide, and her citation record reflects her enduring impact on the field—her guideline alone remains a cornerstone of urologic practice, guiding surgeons in the safe and effective treatment of staghorn calculi.
Research Focus
Key Achievements
Top Papers
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