Marcus Frohme

Technical University of Applied Sciences Wildau

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About

Dr. Marcus Frohme is a leading researcher in the field of cyanobacterial biotechnology and synthetic biology, with a particular focus on developing robust, industrially-relevant strains and high-throughput screening methodologies. His work addresses critical bottlenecks in the commercial cultivation of phototrophic organisms, especially for biofuel and bioproduct applications. Dr. Frohme’s major contributions include the creation and genetic characterization of thermo-tolerant *Synechocystis* sp. PCC6803 strains through adaptive evolution, a foundational study that has garnered 35 citations and provides key insights into the genetic basis of heat shock response. Complementing this, he developed a high-throughput cultivation and screening platform specifically for unicellular phototrophs (31 citations), a pivotal tool that enables parallel, miniaturized, and cost-efficient processing of microalgae and cyanobacteria samples. This platform has significantly accelerated the pace of strain selection and process optimization. Through these innovative approaches, Dr. Frohme has established himself as a key figure in bridging fundamental cyanobacterial genetics with practical, scalable solutions for sustainable biotechnology.