Marcello Simonini

Papers

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About

Marcello Simonini is a leading researcher in neurorehabilitation, with a particular focus on optimizing recovery for patients with severe acquired brain injury. His work centers on the intersection of early mobilization, robotic-assisted therapy, and the physiological mechanisms underlying neurological recovery. Simonini’s most cited study, "Effect of verticalization with Erigo® in the acute rehabilitation of severe acquired brain injury" (2019), has garnered 20 citations and represents a pivotal contribution to the field. In this work, he demonstrated that early verticalization using the Erigo® tilt-table with integrated stepping can significantly improve outcomes in patients with severe brain injury, challenging traditional conservative approaches to acute care. His research provides critical evidence for the safety and efficacy of early, intensive mobilization, influencing clinical protocols in intensive care units and rehabilitation centers worldwide. Simonini’s work is notable for bridging the gap between engineering and clinical practice, offering practical, evidence-based solutions that enhance functional recovery and reduce long-term disability. His contributions continue to shape best practices in neurorehabilitation, making him a key figure for students and clinicians interested in cutting-edge recovery strategies.