Manuela Ingrosso
University of Chieti-Pescara, Agenzia Sanitaria Regionale Abruzzo
Papers
6
Total Citations
227
H-Index
4
About
Manuela Ingrosso is a leading urologic surgeon and researcher whose work centers on optimizing surgical outcomes in robot-assisted partial nephrectomy (RAPN) for kidney cancer. Her primary research focus is the delicate balance between oncologic control and renal function preservation, specifically investigating the impact of renal artery clamping during surgery. Ingrosso is best known for her pivotal role in the CLOCK (CLamp vs Off Clamp the Kidney) randomized controlled trial, a landmark multicenter study that has fundamentally shaped the debate on ischemic damage during partial nephrectomy. Her most cited work, the 2021 publication of the CLOCK trial’s functional outcomes (103 citations), provides critical evidence comparing on- vs off-clamp techniques. She has also authored key analyses on predictors of intraoperative clamp transition and the role of warm ischemia time, using radionuclide renal scans for precise functional assessment. With cumulative citations exceeding 220, Ingrosso’s rigorous, evidence-based contributions have directly informed surgical decision-making, helping urologists worldwide minimize renal injury while maintaining safety. Her work stands as a cornerstone in the evolution of nephron-sparing surgery.
Research Focus
Key Achievements
Top Papers
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