Manuel Maestre‐Reyna
Papers
1
Total Citations
14
H-Index
1
About
Manuel Maestre‐Reyna is a structural biologist whose research centers on membrane protein biology and the molecular mechanisms of bacterial pathogenesis. His work has been instrumental in understanding how integral membrane proteins enable pathogens like *Helicobacter pylori* to survive extreme acidity and colonize the human stomach. His most cited study, "Expression screening of integral membrane proteins from *Helicobacter pylori* 26695" (2007, 14 citations), systematically tackled the challenging task of expressing and purifying these hydrophobic proteins, which constitute roughly one-quarter of the pathogen's proteome. This foundational work provided critical tools for downstream structural and functional studies, shedding light on the unique molecular adaptations that make *H. pylori* such a successful mucosal pathogen. By addressing the technical hurdles of membrane protein research, Maestre‐Reyna has contributed to a deeper understanding of host-pathogen interactions and potential therapeutic targets. His research continues to bridge the gap between protein expression screening and the structural biology of disease-relevant membrane proteins, making him a key figure in the study of bacterial virulence factors.
Research Focus
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Top Papers
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