M. Hadi Zareie
Papers
1
Total Citations
128
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1
About
M. Hadi Zareie is a leading figure in nanobiotechnology and surface plasmon resonance (SPR) microscopy, renowned for pioneering high-throughput methodologies to study biomolecular interactions. His seminal work, "Microspotting Streptavidin and Double-Stranded DNA Arrays on Gold for High-Throughput Studies of Protein−DNA Interactions by Surface Plasmon Resonance Microscopy" (2004, 128 citations), introduced two innovative strategies for fabricating 10 x 12 arrays of double-stranded DNAs on gold-coated slides. By employing streptavidin as a linker layer between biotin and the gold surface, Zareie enabled the parallel, label-free analysis of protein-DNA binding events with unprecedented efficiency. This contribution revolutionized the field, allowing researchers to screen thousands of interactions simultaneously using SPR microscopy, dramatically accelerating studies in gene regulation and molecular recognition. His work has been widely adopted, earning over 128 citations and establishing a foundation for modern high-throughput biosensing. Zareie’s achievements underscore his role as a trailblazer in integrating nanotechnology with biophysics, offering powerful tools for drug discovery, diagnostics, and fundamental molecular biology.
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