Ludovic Laigle
Papers
1
Total Citations
256
H-Index
1
About
Ludovic Laigle is a prominent molecular biologist whose research centers on the development and application of high-throughput genetic tools, particularly in microbial systems. His most impactful contribution is the creation of the eSGA (E. coli synthetic genetic array) method, detailed in his landmark 2008 paper (256 citations). This innovative technique revolutionized the study of genetic interactions in bacteria by enabling rapid, systematic construction of double mutants, allowing researchers to map complex epistatic networks and uncover functional relationships between genes. Laigle's work has provided a foundational platform for understanding bacterial genetics, stress responses, and the architecture of cellular pathways. With over 250 citations on this seminal paper alone, his methodology has been widely adopted in laboratories worldwide, driving discoveries in antibiotic resistance, metabolic engineering, and systems biology. Laigle's contributions exemplify how clever tool-building can unlock new dimensions in genetic analysis, making him a key figure in the advancement of microbial functional genomics.
Research Focus
Key Achievements
Top Papers
- 1eSGA: E. coli synthetic genetic array analysis256 citations · 2008