Luca Berdondini

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About

Luca Berdondini is a leading figure in neuroengineering, whose work bridges microtechnology, electrophysiology, and computational neuroscience. His primary research focuses on developing high-density microelectrode arrays (HD-MEAs) for in vitro and in vivo neural interfaces, enabling unprecedented spatiotemporal resolution in recording and stimulating neuronal activity. A key contribution is his pioneering role in the NeuroBIT project, which advanced "embodied in vitro electrophysiology" by integrating cultured neural networks with closed-loop feedback systems—a foundational step toward understanding neural computation in realistic, interactive environments. This work, cited over 40 times, exemplifies his drive to merge biological neural networks with artificial systems. Berdondini’s impact is further underscored by his development of CMOS-based MEAs, which have revolutionized the study of network dynamics, plasticity, and drug screening. With hundreds of citations across his portfolio, his innovations have been instrumental in shaping modern neuroprosthetics and brain-on-chip technologies. His achievements include leading the European BrainScaleS project and receiving multiple grants for high-resolution neural interfacing, cementing his reputation as a visionary in the field.