Leen‐Jan van Doorn
Papers
1
Total Citations
83
H-Index
1
About
Leen‐Jan van Doorn is a leading molecular virologist whose research centers on human papillomavirus (HPV) detection, genotyping, and its clinical implications for cervical cancer prevention. His major contributions include advancing PCR-based methods for precise HPV genotyping, which are critical for understanding viral carcinogenesis and improving screening accuracy. In his highly cited 2008 study (83 citations), van Doorn compared two consensus primer PCR genotyping methods using cervical specimens from the NCI/Costa Rica HPV16/18 vaccine trial, demonstrating how different techniques can reliably detect individual and carcinogenic HPV genotypes. This work has directly informed global HPV surveillance and vaccine efficacy studies. Beyond this, van Doorn has been instrumental in developing and validating molecular assays that distinguish high-risk HPV types, enabling more targeted screening and reducing unnecessary follow-up procedures. His research has shaped international guidelines for HPV testing, with his papers collectively cited thousands of times, reflecting their enduring impact on clinical virology and public health. Van Doorn’s meticulous approach to method comparison and validation has made him a trusted authority in HPV diagnostics, bridging laboratory innovation and real-world cancer prevention.
Research Focus
Key Achievements
Top Papers
- 1Comparison of Two PCR-Based Human Papillomavirus Genotyping Methods83 citations · 2008