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About

Dr. Lauren Zeise is a preeminent figure in environmental health and toxicological risk assessment, whose work has fundamentally reshaped how chemical hazards are evaluated for public safety. Her primary research areas include computational toxicology, quantitative risk assessment, and the development of alternative testing strategies that reduce reliance on animal models. Dr. Zeise is best known for her pivotal role in the landmark 2007 National Academy of Sciences report, *Toxicity Testing in the 21st Century: A Vision and a Strategy*, which has amassed over 1,675 citations. This visionary framework, which she helped author, called for a paradigm shift from traditional animal-based toxicity tests to high-throughput, mechanism-based assays using human cells and computational models. As the Director of the California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA), she has translated this vision into powerful regulatory action, most notably by leading the development of California’s Proposition 65 program. Dr. Zeise’s profound impact lies in bridging cutting-edge science with real-world policy, making her a central architect of modern, human-relevant chemical safety evaluation.