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About

John C. Bailar is a towering figure in biostatistics and public health, whose work has fundamentally reshaped how we understand and regulate environmental and occupational hazards. His most profound contribution is his leadership on the landmark National Academy of Sciences report, *Toxicity Testing in the 21st Century: A Vision and a Strategy* (2010, 1,675 citations). This visionary document catalyzed a paradigm shift in toxicology, moving the field away from slow, expensive, and animal-intensive methods toward high-throughput, mechanism-based, and human-relevant *in vitro* assays. Bailar’s statistical rigor was instrumental in articulating this new framework, which promises greater efficiency and scientific validity in chemical safety assessment. Beyond this seminal report, his career has been defined by incisive analyses of cancer risks from environmental exposures, including groundbreaking work on the health effects of dioxin and ionizing radiation. A former editor of the *Journal of the National Cancer Institute* and a member of the National Academy of Sciences, Bailar’s legacy is that of a rigorous scientist who provided the intellectual foundation for a more modern, predictive, and ethical approach to protecting human health.