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About

Laura Paparella is a leading researcher in nephrology and perioperative medicine, with a focused expertise in the early detection and prediction of acute kidney injury (AKI) and long-term renal function decline. Her work centers on identifying novel biomarkers and functional imaging techniques to improve risk stratification for patients undergoing major surgeries, particularly robotic and partial nephrectomy procedures. In her highly cited 2023 study (18 citations), Paparella pioneered the use of serum biomarkers—including cystatin C and neutrophil gelatinase-associated lipocalin—alongside kineticGFR to enable early AKI detection and forecast long-term eGFR decline after partial nephrectomy. Her 2024 investigation (4 citations) further advanced the field by demonstrating that Doppler-derived renal functional reserve can preoperatively identify patients at elevated risk for postoperative AKI during robotic surgery. These contributions are critical for reducing AKI-related morbidity and mortality, offering clinicians actionable tools to personalize perioperative care. Paparella’s work is widely recognized for bridging biomarker discovery with practical, real-time risk assessment, making her a key figure in the push toward precision nephrology.