Katrina J. Falkenberg
Papers
1
Total Citations
3
H-Index
1
About
Katrina J. Falkenberg is a molecular biologist whose research focuses on the mechanisms of cell death, particularly apoptosis, and the development of high-throughput screening methodologies to dissect these complex biological pathways. Her major contribution lies in the creation and validation of a robust, multiplex cell death assay that enables the simultaneous measurement of viability and cytotoxicity in a single well. This protocol, detailed in her most-cited work (3 citations), was ingeniously integrated with a genome-scale siRNA screening approach, allowing for the systematic identification of genes that cooperate with therapeutic drugs to induce apoptosis. This work provides a powerful tool for functional genomics and drug discovery, enabling researchers to uncover novel genetic dependencies in cancer cell death. Falkenberg’s achievement demonstrates a sophisticated blend of assay development and RNAi technology, offering a scalable platform for investigating the genetic underpinnings of drug sensitivity and resistance, with direct implications for identifying new therapeutic targets in oncology.
Research Focus
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Top Papers
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