Katherine Mudge
Papers
1
Total Citations
15
H-Index
1
About
Katherine Mudge is a molecular diagnostics researcher whose work has centered on advancing quantitative PCR technologies for hematological malignancy monitoring, with a particular focus on BCR-ABL1-associated leukemias. Her most cited contribution, the 2012 study on fast-mode duplex qPCR for BCR-ABL1 molecular monitoring, addressed a critical need in clinical practice by developing an innovative, automated, and harmonized approach to reverse transcription quantitative polymerase chain reaction (RT-qPCR). This work tackled the challenge of standardizing molecular monitoring across laboratories, improving both the speed and reliability of disease-level tracking in patients undergoing treatment. Mudge’s research has helped refine the sensitivity and reproducibility of qPCR as a tool for minimal residual disease detection, directly impacting clinical decision-making in chronic myeloid leukemia management. Her contributions to assay automation and duplex design have been cited 15 times, reflecting their practical value in translational hematology. By focusing on harmonization and innovation in molecular monitoring, Mudge has supported the broader goal of making precision diagnostics more accessible and consistent, ultimately aiding clinicians in delivering more personalized, response-guided therapies for patients with BCR-ABL1 malignancies.
Research Focus
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Top Papers
- 1