Karin Lanthaler
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1
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82
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1
About
Karin Lanthaler is a leading researcher in the fields of pharmacogenomics and cellular drug transport. Her work has fundamentally reshaped our understanding of how drugs enter cells, moving beyond the traditional model of passive diffusion to reveal the critical role of carrier-mediated uptake. Her most cited study, "Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast" (2011, 82 citations), systematically screened the entire yeast genome to identify the specific membrane transporters responsible for the cellular uptake of various pharmaceutical compounds. This landmark contribution provided a comprehensive framework for predicting drug permeability and bioavailability, with profound implications for drug design and personalized medicine. By demonstrating that drug uptake is predominantly carrier-dependent, Lanthaler’s research has opened new avenues for targeting transport mechanisms to improve therapeutic efficacy and reduce toxicity. Her work remains a cornerstone for researchers studying drug absorption, transporter biology, and the molecular basis of pharmacological response.
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